diabetes
Credit: CC0 Public Domain

Older Californians who live in communities with poor air quality, even those who engage—as recommended—in physical activities but do so outdoors, have a higher risk of Type 2 diabetes, a complex and chronic metabolic disorder caused by insulin resistance and cell dysfunction.

Although development of has typically been related to obesity and physical inactivity, its causes are complex; recent research has suggested that , including air pollution, also play a major role, said Dr. Beate Ritz, a UCLA Fielding School of Public Health professor of epidemiology and who has studied the impact of ozone (O3), a common element of air pollution, on .

“The O3-related risk of developing diabetes was 1.5 times higher in the higher-outdoor activity group, and even in the lower activity group, there is an observably higher risk compared with those living in less polluted communities,” said Ritz, a co-author of the research, who also serves as a professor of neurology at UCLA’s David Geffen School of Medicine. “Physical activity is well known and widely recognized for its , but the beneficial effects that outdoor have on human may have to be weighed against the detrimental impacts of air pollution in areas affected by high pollution levels.”

The study, published in the September edition of the peer-reviewed journal Environmental Health Perspectives.

The researchers, from four different University of California campuses (UCLA, Berkeley, Irvine, and San Francisco), focused on residents of a six county area surrounding Sacramento, all older Mexican-Americans (60 years and up) who enrolled in the Sacramento Area Latino Study on Aging, or SALSA. The counties include Placer, Sacramento, Solano, Sutter, Yolo, and Yuba, although the researchers say the increased vulnerabilities are not limited to the region, or those surveyed.

“Mexican Americans are the fastest growing segment of the U.S. population, have a high prevalence of diabetes, and are also among the most highly air pollution-exposed populations in California,” said Dr. Mary N. Haan, professor emeritus at the University of California, San Francisco, and the principal investigator on the SALSA study, which began in 1998. “Yet, thus far we are not aware of any studies in the U.S. that have explored the relationship between O3 exposure and diabetes, or evaluated whether out-door physical activity modifies associations between O3 and diabetes in this population.”

The researchers reviewed the health information recorded during the surveys, which continued until 2007 on a regular basis, and the pollution, air quality, and traffic levels in the same neighborhoods. They found that of almost 1,800 individuals surveyed, 186 newly developed diabetes.

“Although epidemiological evidence is limited, experiments suggest that ozone exposures may induce insulin resistance, which contributes to diabetes,” said Dr. Yu Yu, a Fielding School researcher and co-author of the study. “In turn, lab experiments have shown that people engaging in physical activities outdoors, and so breathing more heavily, while exposed to ozone, may be affected adversely owing to the increased inhalation of .”

The individuals who developed diabetes lived in communities with higher ozone exposure, and those who were more likely to exercise outdoors, defined as gardening and yardwork, walking, swimming, or dancing; hunting, camping, and boating; and outdoor sports, including golf were at higher risk.

“Sadly, what this makes clear is that even those Californians who are doing the right thing when it comes to health and wellness are at risk of diabetes because of ,” said Dr. Jason G. Su, a co-author and researcher at the University of California, Berkeley. “These findings are of great relevance for public health protection. Policies and strategies are needed to reduce ozone exposure in communities to guarantee that the health benefits from physical activity are not diminished by pollution exposure, especially in vulnerable populations.”

Methods:

The team analyzed the health histories of more than 1,000 Mexican-American participants from the Sacramento Area Latino Study on Aging (SALSA), conducted from 1998 to 2007. Ambient Ozone (O3) exposure levels were modeled with a land-use regression built with saturation monitoring data collected at 49 sites across the Sacramento metropolitan area. Using proportional hazard models, researchers estimated the risk of developing incident diabetes based on average O3 exposure modeled for 5-years prior to incident diabetes diagnosis or last follow-up. Further, the team investigated whether higher vs. lower levels modified the association between O3 exposure and diabetes.


Study shows that regular physical activity is an effective strategy to prevent type 2 diabetes


More information:
Yu Yu et al, Ozone Exposure, Outdoor Physical Activity, and Incident Type 2 Diabetes in the SALSA Cohort of Older Mexican Americans, Environmental Health Perspectives (2021). DOI: 10.1289/EHP8620

Provided by
UCLA Fielding School of Public Health

Citation:
Ozone exposure link to the development of type 2 diabetes (2021, September 24)
retrieved 24 September 2021
from https://medicalxpress.com/news/2021-09-ozone-exposure-link-diabetes.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

Source:Medicalxpress

You May Also Like

Uber asks CDC to designate its drivers and delivery workers as essential

Uber has asked the CDC to designate its ride-hail and delivery drivers…

Crowd of 60 anti-vaxxers swarm staten island food court in a protest against NYC vaccine mandate

Anti-vaxxers: Dozens of anti-vax demonstrators swarmed a food court in New York…

Six in 10 teen girls feel ‘persistently sad or hopeless’, up 60% in a decade

The portion of teenage girls contending with severe depression has reached its…

NHS insists controversial move to slash cancer targets down from 10 to THREE will see patients diagnosed and treated quicker despite huge backlash

The NHS has vowed to diagnose and treat cancer patients quicker after…